MEASUREMENF LEVEL CD4 AND CD8 ,CD44OF TOXOPLASMA GONDIIIMMNOCOMPROMISEDPATIENTS IN KIRKUK CITY

Abstract

The current study is aimed to investigate the prevalence of toxoplasmosis in immunosuppressed people by using serological
methods (ELISA) and genetic methods polymerase chain reaction (PCR) it also studies their effects on enzymes and liver
functions. The study included the collection of 250 blood samples from disease groups (patients with rheumatism who are
taking immunosuppressive therapy, patients with Patients with cancerous disease, patients with pulmonary tuberculosis,
patients with diabetes and patients with thalassemia). The study also collected samples from healthy people.It was also noted
that CD4 T cells recorded the highest significant value in patients with pulmonary tuberculosis, followed by the healthy group,
then the rest of the other study groups.While the T cells recorded CD8 the highest significant value in the healthy group and its
level did not differ from the group of patients with tuberculosis, while the significant values were low in the rest of the groups.
While CD44 T cells recorded the highest significant value in the group of patients with pulmonary tuberculosis, followed by the
healthy group and its value decreased significantly in the rest of the groups.finaly, It was also noted that the rheumatoid factor
recorded the highest significant value in both of the groups of patients with rheumatism and cancer, and it decreased
.significantly in the rest of the study groups