OUTCOMES OF NON OPIOID VERSUS OPIOID BASED GENERAL ANESTHESIA IN ENDOSCOPIC SINUS SURGERIES

Abstract

Background : Functional endoscopic sinus surgery is a standard procedure for the treatment of chronic sinusitis.
This procedure is associated with mild to moderate postoperative pain, which is related to both surgical and nasal
packing . Routine analgesic treatment is usually based on non-opioid analgesics with rescue opioids. However,
there is no consensus concerning the optimal analgesic regimen after endoscopic nasal surgery and an opioidoriented treatment is still often used. So the aim of this study was to compare Opioid Free versus Opioid Based
General Anesthesia outcomes in Functional Endoscopic Sinus Surgeries.
Patients and methods: Patients were divided into 2 equal groups : Group 1: Opioid free group: (Group OFA) 22
participants received , Group 2: Opioid based group: (Group OBA) 22 participants. All participants were
subjected to medical history, complete clinical examination and premedication and routine laboratory
investigations.
Results: There was no statistical significant difference between the studied groups regarding the Mean arterial
pressure, Oxygen saturation and need for analgesia. Duration of stay in post anesthesia care unit was
significantly shorter in OFA Group than OBA Group OBA Group was significantly associated with higher VAS
score at 6-, 10- and 12-hours post-operative.
Conclusion : OFA provided satisfactory intraoperative analgesia and control of surgery-induced pressor
reflexes. Also, the perioperative safety and efficacy of the opioid-free anesthesia techniques provided for
Functional Endoscopic Sinus Surgeries with good postoperative analgesia and other postrecovery criteria.