A REVIEW ON MALARIA, CONTROL&CHALLENGE STRATEGIES

Abstract

In India accounts for about 70% of WHO's Southeast Asian malaria. More than 2 million cases, approx 1,000 deaths
are reported annually from malaria, due to the recognition of many ecotypes paradigms of malaria, the risk of
malaria transmission within the state is heterogeneous and variable.This latest report draws on data from 87
countries and territories with ongoing malaria transmission. The high-exposure population of 4,444 is a population
living in forest areas such as Orissa, Jharkhand, Madhya Pradesh, Chhattisgarh, and northeastern states, and
accounts for most of the morbidity and mortality of malaria. World Health Organization (WHO) reported that 229
million cases and 409 thousand deaths from malaria occurred in 2019. The pattern of clinical manifestations of
severe malaria has also changed, with multiple organ failure more common in falciparum malaria, but there are
reports of vivax malaria with severe symptoms.The reported estimated morbidity-mortality gap, it is necessary to
estimate actual malaria. Artemisinin-based combination therapies (ACTs), are critical tools in reducing the global
burden of malaria, Only 45% (99/221) of articles with therapeutic efficacy as a primary outcome and performing
molecular correction reported corrected efficacy outcomes calculated in a way consistent with WHO
recommendations. The World Health Organization carries out a malaria control program on a global scale, focusing
on local strengthening of primary health care, early diagnosis of the disease, timely treatment, and disease
prevention. Globally, the burden of malaria is lower than ten years ago. However, in the last few years, there has
been an increase in the number of malaria cases around the world. In this review, discuss about the host immune
response in malaria, analyzing the latest studies on the roles of pro- and anti-inflammatory cytokines. To achieve
sustainable control over malaria, healthcare professionals will need a combination of new approaches and tools, and
research will play a critical role in development of various novel strategies