AMPHIPHILIC DRUG DELIVERY SYSTEMS-PHYTOSOMES
DOI:
https://doi.org/10.48047/Keywords:
Drug delivery, Phytosome, Phosphotidylcholine (PC), Phospholipids complex, Bioavailability, Flavonoids, Liposomes.Abstract
The term “Phyto” means plant while “some” means cell-like. Phytosome is a novel drug delivery technique which contains
phytoconstituents of herbal extracts. Preparation of phytosomes involve in the complexation between phytoconstituents and
phospholipids especially with phosphotidylcholine which produces lipid stable molecular complexes. Phytosomes have water
soluble inner layer and lipophilic outer layer. Phytosomes have high pharmacokinetic and pharmacodynamic properties. They
have improved bioavailability when compared to other conventional herbal extracts. They have valuable role in
pharmaceutical industries. Phytosomes can be supplied as natural digestive aids as they acts as antioxidants, hepatoprotective
agents, anticancer agents and used as carriers for water soluble and lipid soluble nutrients.
