To Compare The Efficacy of Weekly Azathioprine Pulse (WAP) And Betamethasone Oral Mini Pulse (BOMP) in The Treatment of Alopecia Areata.

Abstract

Background &Method: This study is done with an aim to compare the efficacy of weekly
azathioprine pulse (WAP) and betamethasone oral mini pulse (BOMP) in the treatment of
alopecia areata.Department of Dermatology,Venereology &Leprology, MDM Hospital,
Jodhpur. Sample size of total 60 patients, 30 in each group Study duration of 01 year. Sixty
patients of clinically diagnosed alopecia areata attending the skin department of Dr. S. N.
Medical College, Jodhpur.
Result:According to table at 12th week of treatment In group I, 6.67% patients showed poor
response, 13.33% of patients showed moderate response, 13.33% of patients showed good
response and 66.67% of patients showed excellent response to the treatment. In group II,
none of the patients showed poor response and moderate response, 3.33% of patients showed
good response and 96.67% of patients showed excellent response to the treatment. Test of
significance showed p value <0.05 it meant that there was significant difference in the groups
regarding response to therapy; group II response was better than group I.
Conclusion:In the present study, the peak age of onset was seen in the young adult age group
between 15-30 years (53.3%). 15. SALT response was statistically significant at 18th week
and 24th week which means that there was significant difference between the decreases in
SALT score to reduce to its 75% of the original value in both the groups. Group II showed
significant improvement during 18th week and 24th week.