Comparison of microalbuminuria w ith hs-CRP and low density lipoprotein levels in nondiabetic, nonhypertensive myocardial infarction patients

Authors

  • B. K. Manjunatha Goud, Bhavna Nayal , Oinam S. Devi , R. N. Devaki , S. S. Avinash , T. G. Satisha , C. V. Raghuveer Author

Keywords:

Low density lipoprotein cholesterol, microalbumin, myocardial infarction, Non diabetics

Abstract

Introduction: Microalbuminuria (MA), defined as urine albumin to urine creatinine ratio (UACR) of 30 to 300 mg/G of creatinine, is an established risk factor for cardiovascular morbidity and mortality and for endstage renal disease in individuals with an adverse cardiovascular risk profile such as those with hypertension or/and diabetes mellitus. Materials and Methods: Thirty five patients were included in the study and equal number of age- and sex-matched controls were also included. 2 ml of venous blood was collected for hs-CRP determination and early morning mid stream urine sample was collected under strict aseptic precautions. The lipid profile was estimated in cobas autoanalyzer. Results:There was significant increase in levels of Low density lipoprotein (LDL) cholesterol, microalbumin, and hs-CRP (P< 0.001) in patients with myocardial infarction compared to healthy controls. Conclusion: Therefore, MA and hsCRP evaluation may have potential role in improving cardiovascular risk prediction, when used along with traditional lipid profiles.

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Author Biography

  • B. K. Manjunatha Goud, Bhavna Nayal , Oinam S. Devi , R. N. Devaki , S. S. Avinash , T. G. Satisha , C. V. Raghuveer

    Introduction: Microalbuminuria (MA), defined as urine albumin to urine creatinine ratio (UACR) of 30 to
    300 mg/G of creatinine, is an established risk factor for cardiovascular morbidity and mortality and for endstage renal disease in individuals with an adverse cardiovascular risk profile such as those with hypertension or/and diabetes mellitus. Materials and Methods: Thirty five patients were included in the study and equal number of age- and sex-matched controls were also included. 2 ml of venous blood was collected for hs-CRP determination and early morning mid stream urine sample was collected under strict aseptic precautions. The lipid profile was estimated in cobas autoanalyzer. Results:There was significant increase in levels of Low density lipoprotein (LDL) cholesterol, microalbumin, and hs-CRP (P< 0.001) in patients with myocardial infarction compared to healthy controls. Conclusion: Therefore, MA and hsCRP evaluation may have potential role in improving cardiovascular risk prediction, when used along with traditional lipid profiles. 

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Published

2012-09-28

Issue

Vol. 3 No. 4 (2012): volume 3 issue 4 (2012)

Section

Articles