Comparison of the Efficacy of Intravenous (IV) Infusion of Dexmedetomidine and Intravenous (IV) Infusion of Nitroglycerine for Controlled Hypotensive Anaesthesia in Elective Spine Surgeries

Abstract

BACKGROUND
Induced hypotension limits intra-operative blood loss to provide better visibility of the surgical
field and diminishes the incidence of major complications during spine surgeries.
Nitroglycerine (NTG) is a well-established vasodilator that acts by reducing increasing the
venous capacitance and reducing preload and cardiac output, thereby reducing the arterial
blood pressure and dexmedetomidine, a selective α2 agonist has sympatholytic action and thus
induce hypotension, so these 2 drugs have been used in this study to induce hypotensive
anaesthesia.