THROMBOLYSIS WITH RECOMBINANT TISSUE PLASMINOGEN ACTIVATOR IN RURAL INDIA: A PROSPECTIVE STUDY ON OUTCOMES AND BARRIERS IN ACUTE STROKE CARE

Authors

  • Ahamed Subir H, Jithesh TK, PA Fazal Ghafoor Author

DOI:

https://doi.org/10.48047/

Keywords:

Acute ischemic stroke, Thrombolysis, Recombinant tissue plasminogen activator, Stroke management, Rural healthcare, Modified Rankin Scale, Stroke outcomes, Healthcare disparities, Socioeconomic barriers, Rural India, Stroke treatment accessibility, Tertiary care

Abstract

This study investigates the use of recombinant tissue plasminogen activator (rtPA) for acute 
ischemic stroke in a cohort of patients from rural India. Background: Despite the global burden 
of stroke as a critical driver of disability and mortality, access to timely thrombolytic therapy 
continues to be limited in rural settings due not only to socioeconomic factors but also 
to logistical barriers. The clinical profile, outcomes and challenges of rtPA treated stroke 
patients: A hospital-based study from a rural tertiary center of Malabar, Kerala. Methodology: 
The study was a prospective, observational design, and 28 patients presenting within the time 
window for rtPA were included. 

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Published

2024-11-01