THROMBOLYSIS WITH RECOMBINANT TISSUE PLASMINOGEN ACTIVATOR IN RURAL INDIA: A PROSPECTIVE STUDY ON OUTCOMES AND BARRIERS IN ACUTE STROKE CARE
DOI:
https://doi.org/10.48047/Keywords:
Acute ischemic stroke, Thrombolysis, Recombinant tissue plasminogen activator, Stroke management, Rural healthcare, Modified Rankin Scale, Stroke outcomes, Healthcare disparities, Socioeconomic barriers, Rural India, Stroke treatment accessibility, Tertiary careAbstract
This study investigates the use of recombinant tissue plasminogen activator (rtPA) for acute
ischemic stroke in a cohort of patients from rural India. Background: Despite the global burden
of stroke as a critical driver of disability and mortality, access to timely thrombolytic therapy
continues to be limited in rural settings due not only to socioeconomic factors but also
to logistical barriers. The clinical profile, outcomes and challenges of rtPA treated stroke
patients: A hospital-based study from a rural tertiary center of Malabar, Kerala. Methodology:
The study was a prospective, observational design, and 28 patients presenting within the time
window for rtPA were included.