To determine the hematological findings & coagulation profile in patients with bleeding manifestations

Abstract

Background & Method: The aim of study is to determine the hematological findings &
coagulation profile in patients with bleeding manifestations. Bleeding time is a blood test that
looks at how fast small blood vessels close to stop bleeding. This test helps diagnose bleeding
problems. Pre-requisites-Certain medications including dextran, nonsteroidal antiinflammatory drugs (NSAIDs), and salicylates (including aspirin) may change the test results.
So the patient should be told to stop taking these medicines if any, a few days before the test.
Result: The most prevalent hematological disorder is found to be Idiopathic
thrombocytopenic purpura (23%), aplastic anemia (14%), Systemic causes (11%) while
Myelodysplastic syndromes & Hemophilia have equal prevalence rate (7%). Among the
bleeding disorders platelet disorders (74%) are more common than coagulation disorders
(15%). Inherited bleeding disorders involve males (17%, n=104) more commonly than
females (6%, n=96). However statistically no gender association could be obtained in
inherited bleeding disorders as P = 0.125 (P > 0.05).
Conclusion: Study shows the highest prevalence of bleeding disorders that is 27% in the
age group of 11-20 years while lowest 5% above 60 years of age. Males are found to be
affected slightly more commonly (52%) than females (48%). The most prevalent
hematological disorder is Idiopathic thrombocytopenic purpura (23%) followed by aplastic
anemia (14%), Systemic causes (11%) Myelodysplastic syndromes (7%). & Hemophilia
(7%). Of all the bleeding disorders, platelet disorders (74%) are more common than
coagulation disorders (15%).