EVALUATION OF OXIDATIVE STRESS & TOTAL ANTIOXIDANT CAPACITY, OXIDIZED LDL IN ADULT SMOKERS
DOI:
https://doi.org/10.48047/Keywords:
oxidised low density lipoprotein, total antioxidant capacity malondialdehyde and smokers.Abstract
Introduction: Tobacco is very harmful to our body. It contains five thousand of injurious chemicals
injurious for our body and heart and cause various diseases like lung, oral cancers and obstructive
pulmonary diseases. It is a serious threat for health. Smoking causes deaths. India ranks second as a
cause of death in the world.
Objectives of the study: to determine the levels of MDA as marker of oxidative stress, total
antioxidant capacity and oxidized LDL in adult smokers.
Methodology: Fasting Venous blood (5 ml) was collected under taking aseptic precautions and the
serum was separated used for the estimation of Oxidised LDL (Ox-LDL), total antioxidant capacity
(TAOC) and malondialdehyde (MDA) .
Results: In the present study, Ox-LDL and MDA were significantly increased & TAOC (Total
antioxidant capacity) was significantly decreased (p < 0.005) in smokers compared to non-smokers.
Conclusion: Our study provides the evidence that total antioxidant capacity is decreased in smokers
as compared to healthy controls. Levels of MDA and Ox-LDL is increased in smokers as compared
to healthy controls.
