A Prospective Comparative Study of Oral Clonidine and Oral Midazolam as Premedicants for General Anesthesia: An Original Research

Authors

  • Dr. Voviliveni Srikala, Dr Chandrashekhar Botla, Dr. Bheemanadhuni Anusha, Dr. Potlapelly Vasu Prakash, Dr Sreenivas Azmeera Author

DOI:

https://doi.org/10.48047/

Keywords:

premedication, oral clonidine, oral midazolam, general anesthesia, comparative study

Abstract

Background: Premedication enhances patient comfort during general anesthesia. Clonidine 
and midazolam, both sedatives, lack a comparative safety and efficacy analysis in this 
context.
Methods: A trial compared clonidine and midazolam effects as pre-anesthetics. 100 
orthopedic surgery patients at a tertiary care center were randomly given one. Standardized 
protocols guided administration. Outcomes included sedation, anxiety reduction, 
hemodynamic stability, adverse effects, and post-anesthesia recovery time. 

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Published

2024-03-01