VIT D STATUS AND DETERMINANTS IN INDIAN CHILDREN AND ADOLESCENTS: A MULTI-CENTRE STUDY
DOI:
https://doi.org/10.48047/Keywords:
Vitamin-D, Children, Adolescents, Indian, Anthropometry, Liquid Chromatography, Tandem-Mass Spectrometry.Abstract
Research on vitamin D status in Indian children has been confined to studies
conducted on small samples from certain regions and using non-standard techniques to
quantify 25(OH)D3. Vitamin D insufficiency was observed in this multicenter research that
used a standardized technique to evaluate 25(OH)D3 concentrations from dried blood spots
(DBS) in children and adolescents from 5 to 18 years old in India. This school-based crosssectional observational research used a multi-stage stratified random sampling technique. We
picked a city and its surrounding hamlet from six states in India, which span a lot of ground.
Data was gathered on demographics, anthropometry, body composition, food intakes, and
DBS samples. Liquid chromatography with tandem-mass spectrometry was used to evaluate
25(OH)D3 in DBS. A total of 2450 youngsters had their vitamin D level checked, with a
subset (n = 672) having extra data obtained for the purpose of evaluating predictors. In the
study, 36.8% of participants had adequate vitamin-D levels (> 50 nmol/L), with greater
concentrations seen in rural respondents and boys (p < 0.05). The mean vitamin-D
concentration was 45.8 ± 23.9 nmol/L.
