A Study On Neurological Manifestations In HIV Patients

Abstract

India ranks third globally in terms of the magnitude of its HIV (human immunodeficiency virus) epidemic. Despite the proper administration of anti-retroviral therapy (ART), patients infected with HIV still encounter neurological complications. There are several factors that contribute to it, such as insufficient control of HIV replication in the brain, the production of harmful HIV proteins in the brain, a low level of CD4+ T cells at its lowest point, ongoing immune system activation, the presence of other conditions like drug misuse, and the potential harmful effects of certain antiretroviral medications on the brain. HIV has been detected in the brain and cerebrospinal fluid (CSF) of individuals who are infected, regardless of whether they have neurological symptoms