PREPARATION AND EVALUATION OF POLYHERBAL ANTIFUNGAL CREAM

Abstract

During the latter part of the 20th century herbalism has become main stream worldwide. This is due in part to the
recognition of the value of traditional and indigenous pharmacopeias, the incorporation of some derived from these
sources into pharmaceuticals, the need to make health care affordable for all and the perception that natural
remedies are somehow suffer and more efficacious then remedies that are pharmaceutically derived. Through the
world, there has been an increasing incidence of fungal infections, and because of drug resistance and toxicity
associated with long term treatment with antifungal drugs, search for new drugs to treat fungal infection is ongoing.
The aim of the present study was to formulate poly herbal anti-dermatophytic antifungal cream containing extracts
of Sapindus trifoliatus & Manilkara zapota. One general best cream formulation was selected from the standard
books and prepared formulation was evaluated for its efficacy, uniformity, stability and appearance. The final
product was a w/o emulsion cream with suitable appearance and desirable physiochemical stability. Due to the
stability of the extract in the cream formulation, it can be used for treatment of fungal skin infections.