Maternal and foetal morbidity in women with preeclampsia at varying gestational ages and its correlation with placental pathology
DOI:
https://doi.org/10.48047/Keywords:
Early-onset preeclampsia, late onset preeclampsia, maternal outcome, perinatal outcome, placental pathological changes.Abstract
Objective: We examined the effects of early- and late-onset preeclampsia on maternal and perinatal
outcomes as well as compared pathological changes of placenta in these two groups.
Results: Compared with the late-onset group, the early-onset group had higher rates of C-section
(35.29%), Placental Abruption (31.37%), HELLP Syndrome (15.68%) and Disseminated Intravascular
Coagulation (7.84%), stillbirths (29.41%), FGR (13.7%), abnormal Apgar score (35.29%), NICU
admissions (33.3%) and neonatal death (5.88%). The placental pathological changes observed in patients
with hypertensive disorders of pregnancy like retroplacental hematoma, infarction, calcification, decidual
arteriopathy, atherosis were more frequently associated with early onset PE as compared to late onset PE
that has an adverse influence on perinatal outcome even after correcting gestational age.
Conclusion: Present study concluded that the women suffering from hypertensive disorders of
pregnancy and particularly those who were diagnosed with early onset pre-eclampsia bears the major
brunt of the disease and its complications in the form of fetomaternal morbidity & mortality.
