STUDY TO EVALUATE THE EFFICACY OF INDIGENOUS OINTMENT IN ACHIEVING BENEFICIAL EFFECTS ON WOUND CONDITIONS

Abstract

Background: Wounds and their management are fundamental to the practice of surgery and all surgeons depend on wound repair process. Introduction of clinically effective antimicrobial agent has regularly followed by the rapid emergence of strains of bacteria
resistant to them. Present study was aimed to evaluate the efficacy of indigenous ointment in achieving beneficial effects on wound conditions. Material and Methods: Present study was prospective, observational study, conducted in patients aged between 18-65 years, either gender, had wound. An indigenous product ointment was used as a topical agent for dressing, from time of admission till complete wound cover is achieved. Results: This open labelled study involving 50 patients, majority patients were from 26-50 years of age (48 %), were male (63 %) & of non-diabetic aetiology (76 %). In present study, majority wounds were ulcers (40 %) followed by burns (18 %), post-op wounds (16 %), amputation stumps (14 %) & pressure sores (12 %). The mean day of achieving zero slough was 14 days. 26% of the wounds were sterile at the inclusion in the study while rest grew various organisms at inclusion but were sterile at completion. Common organisms isolated were Pseudomonas Aeruginosa (24 %), Staphylococcus Aureus (20 %) & Proteus Mirablis (10 %). In 80 % patients, systemic antibiotics used in conjunction with local agent. In majority of the patient’s wound closure was achieved with split skin grafting (74 5). Only local itching was observed as an adverse reaction (2 %) in present study. Conclusion: This indigenous product is efficient as local agent in achieving beneficial effects on wound healing, highly effective against large spectrum of microbiological flora of wounds, effective in achieving good scar quality.