Evaluation of inflammatory markers in Juvenile-onset Ankylosing Spondylitis (10-18years)

Abstract

Ankylosing Spondilitis is one of a family of chronic inflammatory disorders 
(spondyloarthropathies) primarily affecting peripheral and axial joints of the body. It is considered a "primary" disease because there seems to be no causal event producing it, 
whereas Reiter's syndrome, psoriatic arthritis, enteropathic (intestinal) arthritis, and others, 
are considered "reactive" because they seem to occur as a result of other inflammatory 
conditions (Chen CH et al 2007). As reported in a Harvard Health Letter Special Report, 
apparently Ankylosing Spondilitis has been with humans since the dawn of civilization ( 
Textbook of Internal Medicine, 1989). In 1912, an Egyptologist unearthed a mummy from 
around 2,900 B.C. whose spine was as rigid as a block of stone from the sacrum to the neck.