Immunohistochemical profile of unusual breast lesions

Abstract

Background: It can be difficult to diagnose breast lesions that are unusual. Nonneoplastic lesions, 
benign tumours, and primary and metastatic cancers are some of these lesions. This article describes a 
wide variety of unusual breast tumours that can manifest as breast lumps. This study's objective is to 
present an overview of the variety of uncommon breast abnormalities, particularly malignant tumours.  
Material and Methods: The Siddhartha Medical College's Department of Pathology in Vijayawada 
evaluated 198 cases of breast lesions over a three-year period (August 2016-July 2019), comparing 
histopathological findings with imaging and IHC findings. The lesions identified were both neoplastic 
and non-neoplastic. 18 (35.6%) out of 198 cases of breast lesions were presented with rare findings. 
Results: Out of 198 cases, 189 (95.45%) were neoplastic and 9 (4.54%) were non-neoplastic. Among 
neoplastic lesions, 88 (44.44%) were malignant, 1 (0.5%) was in situ and 100 (50.5%) were benign.