Comparative Study of Serum Levels of Gamma-glutamyl Transferase, Aspartate Aminotransferase (AST), Alanine Transaminase (ALT), AST: ALT, andBilirubin in Patients with Chronic Hepatitis

Abstract

Introduction: Viral hepatitis and other liver-related diseases are mostly difficult to diagnose solely 
based on clinical regimes. Liver damage resultsin alterationsin serum enzyme patterns which have
been used to develop many enzyme-based assays.
Aim and objectives: The major clinical consequences of chronic liver disease can be evaluated by liver 
function tests like bilirubin, gamma- glutamyl transferase (GGT), aspartate aminotransferase (AST), and 
alanine transaminase (ALT). Alanine transaminase and AST changes indicate leakage from damaged 
hepatocytes. The present study was conducted to compare the serum levels of GGT, AST, ALT, AST:ALT 
ratio, and bilirubin in patients with chronic hepatitis.