A Comparative Analysis of Serum Creatinine and Urea in Diabetic and NonDiabetic Individuals

Abstract

Introduction: Diabetes mellitus poses a significant global health challenge due to its implications on various organ systems, particularly kidney function. This study aimed to evaluate serum urea, serum creatinine, and blood sugar levels in individuals (diabetic and non-diabetic), exploring their interrelationships and implications in diabetic nephropathy. Materials and Method: Fifty diabetic and twenty non-diabetic participants were assessed for three months at Bhima Bhoi Medical College and Hospital in Balangir, Odisha, India. Blood samples were collected for urea, creatinine, and blood sugar analysis. Statistical computations were performed to analyze correlations and associations among these biomarkers.
Results: Strong positive correlations were found between blood sugar and serum urea levels in diabetic patients, suggesting a link between glycemic control and kidney function. Serum urea and creatinine emerged as promising markers for assessing renal damage in diabetes. Notably, gender specific differences in serum creatinine levels were observed, warranting further investigation.
Conclusion: Effective blood sugar management plays a crucial role in preventing diabetic nephropathy. Serum urea and creatinine serve as valuable indicators for monitoring kidney function in diabetes. The study underscores the significance of assessing renal health and functioning tests in managing type 2 diabetes and advocates for further research to enhance diabetes care strategies.