Study of maternal risk factors and compare the perinatal outcome in thick and thin meconium stained amniotic fluid

Abstract

Background: Meconium is the first substance secreted from fetal intestines and consist of intestinal epithelial cells, lanugo, mucus, amniotic fluid, bile and water. Its formation begins around 10-12 weeks of gestation and the quantity goes on increasing as the gestational age advances and it is the post-mature baby who is at a greater risk of passage of meconium in utero and its consequences like meconium aspiration syndrome (MAS). Aim & Objective: 1 Study of maternal risk factors and compare the perinatal outcome in thick and thin meconium stained amniotic fluid.2 study the mode of delivery in a labour complicated by meconium stained amniotic fluid. Methods: Study design: Prospective Study. Study setting: Department of Obstetrics and Gynaecology, Rohilkhand medical college and hospital Bareilly Study duration: From November 2022 to November 2023. Study population: All meconium stained amniotic fluid patients admitted in our institute during study period included in the study. Sample size: 50 Results: Majority of cases found in 31-35 years age group 20 cases (40%) followed by above 35 years age group 14 cases (28%), 13 (26%) cases in 26-30 years age group and 4 cases in 18-25 years age group. most of cases found with thin MSAF 24 (48%) followed by moderate thick MSAF 14 (28%) and thick MSAF found in 12 cases (24%). majority of cases presented with post maturity 30 (60%) followed by prolonged labour 31, Anemia 25 cases, IUGR 17,PIH 14 and 8 cases found with oligohydramnios. Most common mode of delivery was LSCS 22 cases followed by AD 18 cases and Normal vaginal delivery observed in 10 cases. majority of cases found Asphyxia 60% followed by meconium aspiration syndrome 12 cases, neonatal pneumonia 8, Early/late onset sepsis 5, persistent pulmonary hypertension found in 4 cases. Mortality 2%. Conclusion: Most common maternal risk factor was post maturity, Majority of cases delivered through LSCS, Perinatal Mortality was 2%.