CORRELATION OF CT SEVERITY SCORE AND LABORATORY PARAMETERS WITH CLINICAL OUTCOME AND COMPLICATIONS IN COVID 19 PATIENTS

Abstract

Introduction:Corona virus disease 2019(COVID-19) is an infectious acute disease associated with significant morbidity and mortality.The disease threatened the whole world in 2020 and 2021 and new cases are reported till date. CT is invaluable in assessing no of bronchopulmonary segments involved in the lung as conventional chest X ray is not sensitive.Several cytokines are released during pathogenesis of the disease which play a pivotal role in dictating the disease outcome.In this study, we aimed to study the correlation between CT score, inflammatory markers with patient’s outcome.
Materials and Methods: A retrospective hospital based study conducted at Sri Manakula Vinayagar medical college and hospital(SMVMCH), tertiary care center located at Madagadipet in rural Puducherry, India.Adult patients who got admitted in SMVMCH with proven COVID 19 infection were chosen as study participants. The study was carried out after obtaining Institutional ethics committee (IEC)clearance. Data pertaining to CT severity score(CTSS), inflammatory markers, duration of hospital staytill discharge or death is collected from all such patients.
Results:CT score was correlated using Pearson Correlation. Sample size(N) was taken as 117. CT score of 7 or less was classified as mild, was seen in 29 patients(24.8%).Moderate Covid was classifiedat a score of 8-17, was seen in 71 patients (60.7%). Severe Covid score of 18 or greater was seen in 17 out of the 117 patients (14.5%). Out of the 117 patients 51.3% of patients stayed in hospital for 7 days, 33.3% stayed in hospital for 14 days, 8.5% stayed in hospital for 21 days, 6.8% stayed in hospital for 31 days.Patients with increased values of CTSS and C reactive protein(CRP)had higher length of hospital stay and increased mortality compared to other patients.49 patients were observed in intensive care for an average duration of 3 days till their oxygen saturation got stabilized at 95% or more and were shifted to ward care.
Conclusion: Increased CTSSwas associated with increased duration of hospital stay and increased mortality. CRP was the marker which had a strong co relation with patient’s outcome and CTSS