To assess the level of lipid parameters and liver enzymes in lipid induced dyslipidaemia

Abstract

Background: Dyslipidaemia, a major contributor to cardiovascular diseases, is rapidly increasing in Asian countries including India. In addition to the cardiovascular system, abnormal lipid levels are also known to cause complications in renal and hepatic systems. The
data regarding dyslipidaemia and its relationship with liver enzymes has threatened. Therefore, this study was conducted to evaluate liver enzyme and dyslipidaemia in lipid induced hepatic diseases.
Methodology: A total of 150 participants (100 males and 50 females) were enrolled in the study. Serum levels of TG, TC, LDL, HDL and liver enzymes including ALT, AST, GGT and ALP were analysed using standard methods. Dyslipidaemia and liver function tests
abnormalities were defined according to the international standard guidelines.
Results: Dyslipidaemia and liver enzyme abnormalities were higher in hypertensive participants than in the healthy participants. About 61% of participants with dyslipidaemia had at least one or more elevated liver enzymes. In regression analysis, an independent association was observed between serum GGT and all lipid components.
Conclusion: Subjects with dyslipidaemia often have a higher chance of having liver diseases than subjects with no dyslipidaemia