THE AUTOLOGOUS PLATELET RICH FIBRIN MATRIX(PRFM) AS CELL THERAPY IN THE TREATMENT OF CHRONIC NON- HEALING ULCERS- A PROSPECTIVE STUDY
DOI:
https://doi.org/10.48047/Keywords:
Platelet rich fibrin, PRF , Non-healing ulcer.Abstract
Background: Non-healing ulcers are a major cause of disability and impairment, interfering with physical and mental well-being of patients chronic non- healing ulcers. They are difficult to manage having longer duration of treatment and increased financial burden. Minimizing the duration of healing can be a major step in rehabilitation of such patients. Platelet rich fibrin (PRF) is a newer modality to hasten wound healing. It is a concentration of platelets suspended in plasma extracted after centrifuging patient’s own blood.
Aim: To study the efficacy of platelet-rich fibrin (PRF) in management of non-healing ulcers.
Methodology- Prospective Study was conducted in the Department of Dermatology, Venereology, and Leprology, Nalanda Medical College and Hospital, Patna.with Sample size of 60 patients over a period of 18 months.
Results: The mean age of cases in our study was 48.41±11.52 years. The average percentage improvement in area and volume was 97.12% and 98.72% respectively. The mean duration of healing was found to be 2.41 weeks. The procedure was safe with no noted adverse events.
Conclusion-PRF is an inexpensive, safe, feasible and effective procedure in the management of non-healing ulcers.
