TO STUDY THE CORRELATION OF RETINAL NERVE FIBRE LAYER AND GANGLION CELL LAYER THICKNESS WITH GLYCEMIC CONTROL IN DIABETIC PATIENTS
DOI:
https://doi.org/10.48047/Keywords:
Diabetic retinopathy, Retinal nerve fibre layer , Ganglion cell layer, Spectral domain optical coherence tomography, Glycosylated hemoglobin.Abstract
Purpose:To study the correlation of retinal nerve fibre layer and ganglion cell layer thickness with glycaemic control in patients of diabetes mellitus
Methods: This cross-sectional study was carried out on 100 eyes of 100patients of type 2 diabetes . Diabetic patients with evidence of macular oedema were excluded. Demographic data and relevant medical details were documented and all study subjects underwent a comprehensive ophthalmic evaluation. Glycosylatedhaemoglobin(HbA1c) was estimated for all individuals using venous blood sample.
Peripapillary RNFL andmacular GC-IPL thickness were assessed for all study participants by SD-OCT (Carl Zeiss Cirrus HD-OCT). Pearson coefficient was used to study the correlation of RNFL and GC-IPL thickness with glycaemic control.
Results:Only a weak negative correlation was seen between glycaemic status and RNFL thickness as well as GC-IPL thickness for both controlled diabetics as well as poorly controlled diabetics. This weak negative correlation was statistically insignificant.
Conclusion:No significant correlation could be established with HbA1c levels either with RNFL thickness or GC-IPL thickness in diabetic patients.
