COMPARISON OF TWO DIFFERENT DOSES OF FENTANYL i.e. 2µg/kg AND 4μg/kg IN ATTENUATING HAEMODYNAMIC RESPONSE TO LARYNGOSCOPY AND INTUBATION

Abstract

Aims and objective-The purpose of this open comparative trial was to compare the efficacy of two different doses of fentanyl, 2ug/kg and 4µg/kg, to attenuate the haemodynamic response to laryngoscopy and intubation. Mateterial and methodsOne hundred and fifty ASA-I patients 18-50 years of either sex were divided into three equal groups (Control group, F2 group and F4 group). All patients had standard protocol for premedication and induction. Pulse, systolic blood pressure, diastolic blood pressure, mean arterial pressure and rate pressure product were recorded at different time intervals and values were expressed as mean ± standard deviation.conclusion Our study confirms previous reports that laryngoscopy and intubation are accompanied by a considerable increase in arterial blood pressure significantly attenuated by intravenous administration of fentanyl.