Assessment of osteoporosis in patients with interstitial lung disease

Abstract

Background: Interstitial lung disease (ILD) is a group of lung disorders characterized by inflammation and scarring (fibrosis) of the interstitium. The present study was conducted to assess osteoporosis in patients with interstitial lung disease.
Materials & Methods: 96 patients with interstitial lung disease of both genders under went a dual‑energy x‑ray absorptiometry scan. Duration of symptoms, previous anti‑tubercular therapy (ATT), diabetes, smokers, SaO2, FVC and steroid use were also recorded. Two
groups were made. Group I was osteoporosis and group II was no osteoporosis group.
Results: Out of 96 patients, males were 58 and females were 38. BMI in group I patients was 23.5kg/m2 and in group II patients was 23.1kg/m2. The mean duration of symptoms was 3.5years in group I and 1.2years in group II. Previous ATT was seen in 6 and 10, steroid use in 15 and 17, diabetes in 7 and 13, ever smokers were 6 and 7 in group I and II respectively. SaO2 was 93.2% and 94.6%, FVC was 72% and 69% respectively. The difference was significant (P< 0.05).
Conclusion: Authors found that half of the patients had osteoporosis. Osteoporosis seems to be a common extra‑pulmonary manifestation of ILD.