Analysis of the Serum Levels of copper and zinc in chronic obstructive pulmonary disease patients

Abstract

Background: The present study was conducted for analyzing of the Serum Levels of copper and zinc in chronic obstructive pulmonary disease (COPD) patients.
Materials & methods:A total of 50 patients with presence of COPD were enrolled. Another set of 50 healthy subjects were enrolled as controls. Patients had different stages of the disease according to GOLD (GOLD II, III and IV). Blood samples were obtained from al the
subjects and was sent to laboratory where copper and zinc levels were evaluated using autoanalyzer.
Results: Mean serum copper levels among COPD patients and controls was 356.8μg/L and 224.7μg/L respectively. While comparing the results statistically, significant results were obtained. Mean serum zinc levels among COPD patients and controls was 2135.1μg/L and
1539.2μg/L respectively. Mean serum zinc levels were significantly higher among COPD patients.
Conclusion: COPD patients are accompanied by significant alteration of serum copper and zinc levels.