ASSESMENT OF LEFT VENTRICULAR HYPERTROPHY IN CHRONIC KIDNEY DISEASE PATIENTS

Abstract

Left ventricular hypertrophy is major cardiovascular finding in CKD patients. The aim of present study is to find out the correlation of left ventricular hypertrophy (LVH) with severity of disease in CKD patients
METHODOLOGY:
 A total of 100 chronic kidney disease patients admitted in government general hospital, Nellore; over a period of two years were taken as study population. Detailed history, clinical evaluation, laboratory investigations, ECG and echocardiography was carried out. The diagnosis of CKD was made on basis of serum creatinine more than 1.5 mg/dl for 3 or more months. Patients with mild, moderate and severe CKD were having serum creatinine level 1.5-3mg/dl, 3-6mg/dl and > 6mg/dl respectively. Glomerular filtration rate (GFR) was calculated by modification of diet in renal disease (MDRD) equation. Cut-off for CKD was taken to be an eGFR <60ml/min / 1.73m2 as per existing guidelines.
RESULTS:
 Out of 100 patients were studied, 62 were males and 38 were females. All patients were selected randomly. Majority of the patients were in the age group was between 51-70 years. In the present study, it was found that left ventricular mass index (LVMI) which reflects LVH showed a progressive rise in severity of renal failure with 13.5 % of mild category of CKD having LVH as compared to 37.8% of moderate category and 48.6% of severe category of CKD.

CONCLUSION:
 In this study, that the patients with CKD have LVH, which was observed more in patients with severe CKD.