INCIDENCE OF ACUTE KIDNEY INJURY IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION

Abstract

Acute kidney damage (AKI) is a complicated disorder with bad prognosis and can be brought on by several illnesses. In India, the morbidity of AKI has grown during the previous few decades from 3/1000 to 17.3/1000. 1 AKI is thought to occur in 5% of all hospitalizations, with related healthcare costs exceeding $10 billion annually, while exact figures are unknown. Rapid loss of renal
performance is the hallmark of acute kidney injury (AKI), which might result in multitude of problems such as fluid imbalance, metabolic acidosis, and uremia. One in five patients who are admitted in hospital for an acute myocardial infarction (AMI) experience an acute kidney damage (AKI). Slight increases in blood creatinine levels are linked to higher rates of death both immediately and later on, longer lengths of stay(LOS), and higher costs. 2 Patients with AMI who also developed AKI had a death rate that was 20– 40 times higher than those who did not develop AKI. However, there is still a lack of knowledge regarding the morbidity, risk factors, and effects of AKI in individuals with AMI. The current criteria for AKI include the Kidney Disease Improving Global Outcomes (KDIGO) Clinical Practice Guidelines for AKI developed in 2012, the Acute Kidney Injury Network (AKIN) criteria developed in 2007, and the Risk Injury Failure Loss End-Stage Renal Disease definition developed in 2004 by the Acute Dialysis Quality Initiative group. 3 KDIGO definition of AKI, which stipulates a rise in serum creatinine as a prerequisite, was used in our investigation. 4