HYPONATRAEMIA AS AN INDEPENDENT PREDICTOR OF SHORT TERMMORTALITY IN HOSPITALISED PATIENTS OF ACUTE ST ELEVATED MYOCARDIAL INFARCTION

Abstract

Introduction: Clinically, myocardial infarction is well-known and is one among the many leading causes of death and disability worldwide, affecting people of all racial and ethnic backgrounds. Any person can be affected by it, and it can have serious negative psychological, financial, and economic ramifications. Acute coronary syndrome is a significant public health issue in both industrialised and emerging nations, and despite studies on diagnosis and treatment over the past four decades, its importance is growing there. Studies today show that there is a decrease in infectious disease, while ischemic heart disease and acute myocardial infarction are rapidly increasing in developing nations due to rising economic development and lifestyle changes that encourage atherosclerosis. Although there exists a significant discrepancy in the resources available to treat acute myocardial infarction in developing nations like India, significant efforts are still required to establish primary preventive activities at the community level. One of the most prevalent electrolyte disorders is hyponatremia. Hyponatremia is the major risk factor for cardiovascular death in heart failure patients. Congestive heart failure, chronic glomerular nephritis, and cirrhosis of liver patients are the most prevalent inpatients with this condition, which is typically diagnosed in the first postoperative week following surgery. Since acute myocardial infarction and heart failure both cause neurohumoral activation, hyponatremia is frequently discovered following myocardial infarction. The rise in serum sodium concentration causes the clinical symptoms of hyponatremia to improve. Although the prognostic significance of hyponatremia in chronic heart failure is well established, it is discovered that there is insufficiency of data in the case of acute myocardial infarction. The purpose of my study is to investigate the prognostic significance of hyponatremia in acute ST-elevated myocardial infarction and to assess how beneficial it is in predicting short-term survival