Study of suspected myocarditis in covid positive ICU patients

Abstract

Background: A novel beta-Coronavirus related to Severe Adult Distress Syndrome, named SARS-CoV was the cause of pandemic with more than 24 million people contaminated. COVID-19, the disease provoked by the virus, resulted in more than 80,000 deaths in quite
200 countries worldwide. Several cardiovascular complications were reported in literature like arrhythmias, myocarditis, pericarditis, heart failure, myocardial ischemia, myocardial infarction, and Takotsubo syndrome. To our knowledge several cases of myocarditis
associated with SARS-CoV-2 have been reported so far; nevertheless, to date, there is a knowledge gap regarding the real prevalence of this cardiac involvement, its pathologic pathway and specific characteristics of patients who experience this complication. Thus, we
will analyze the data of covid 19 cases on the basis of appropriate sample size of the patients admitted in our hospital. Objectives: 1. Study of hospital related outcome of Covid 19 patients with suspected myocarditis, 2. Correlation of NT-PROBNP levels, TROPONIN
T in suspected case of myocarditis with outcomes. Methods: Study Design: Hospital based retrospective study Setting: Patients admitted in ICU in SMS Medical College and attached hospitals Result: Patients with myocarditis had significantly more prolonged hospitalization 14.75±8.53 days as compare to without myocarditis 10.44±4.16 days (P value .009), they had the non-significant values of IL-6 level, NT-pro-BNP and T-troponin patients without myocarditis Conclusion: Myocarditis is a severe cardiac complication in SARS-CoV-2 infection. Present study showed that in COVID-19 patients myocarditis was associated with more severe infection and a higher need for oxygen therapy, a higher rate of cardiac disease, and a longer hospitalization