Serum creatine in COPD: A Case Control Study from SMBT Medical College, Igatpuri, Maharashtra

Abstract

Introduction: Chronic renal failure (CRF) rises in prevalence with age and is frequently associated with chronic diseases such as congestive heart failure and diabetes mellitus. When present as a comorbidity, CRF carries negative prognostic implications and impacts the therapeutic strategy. It is unknown to which extent COPD is associated with CRF and the relationship between renal failure and COPD is largely undescribed.
Objective: To study the role of serum creatine in COPD and non-COPD patients
Methodology: The present case control study was conducted at Department of Medicine, SMBT Medical College, Igatpuri involving 50 cases and 50 controls visiting to Medicine department OPD as well as inpatients admitted in the same department of SMBT Medical
College, Igatpuri during the study period from January 2023 to October 2023.
Results: We included 50 cases and 50 controls in our study. Majority of the cases i.e. 64% and controls i.e. 62% were from 61-70 years age group. Equal number of males (64%) and females (36%) were included in our study. Abnormal levels of serum creatine were seen in 24% of cases and 6% of controls. This difference in the proportion of cases and controls was found to be statistically significant (p<0.05). It means number of cases with abnormal serum creatine were significantly higher compared to controls.
Conclusion: In our study, abnormal levels of serum creatine were seen in 24% of cases and 6% of controls. This difference in the proportion of cases and controls was found to be statistically significant (p<0.05). Our study findings strongly support the association of increased prevalence of CKD in patients with COPD.