Effects of positive acceleration on the metabolism of endogenous carbon monoxide and serum lipid in atherosclerotic rabbits

Abstract

Atherosclerosis (AS), the most important pathologic process leading to cardio- and cerebrovascular diseases, is suggested to be mediated by the increase in the serum lipid, thrombosis, and injuries of the endothelial cells.[1,2] During aviation, a kind of special occupation, pilots may experience an incremental load of acceleration that leads to dramatic stress reactions and hemodynamic changes. The positive acceleration exposure, especially repeated exposure, may cause accumulative adverse stress reactions in the body