TO DETERMINE & COMPARE LIPID & URIC ACID LEVELS ABNORMALITIES IN THE PATIENTS OF PSORIASIS, AND ITS RELATIONSHIP WITH THE SEVERITY OF PSORIASIS

Abstract

Background & Methods: The aim of the study is to determine & compare lipid & uric acid levels abnormalities in the patients of psoriasis, and its relationship with the severity of psoriasis. Total 160 study subjects were divided into two groups, group A comprising 80 apparently healthy controls and group B comprising 80 patients of psoriasis, which is again divided into subgroups on the basis of severity of the disease, group C included mild cases of psoriasis and group D of moderate/ severe cases of psoriasis.
Results: Comparison of Lp(a) in multiple groups, Mean Lp(a) level of group B was higher than group A but it is not statistically significant. Difference in group A and group D were highly significant statistically. Difference between group C and group D were statistically significant.
Conclusion: We suggest early screening with serum lipid profile and uric acid levels in all psoriatic patients at the time of diagnosis and follow-up for evaluating risk of cardiovascular disease and treatment of hyperlipidemia and hyperuricemia to modify and prevent the risk of cardiovascular disease