TO COMPARE THE OUTCOME OF USE OF PRP WITH THAT OF CONVENTIONAL METHODS ON NON-HEALING ULCERS

Abstract

Background & Methods: The aim of the study is to compare PRP with that of conventional methods on non-healing ulcers. All patients in study underwent a detailed history taking including general examination. Under aseptic precautions 20 ml of venous blood was drawn and added to a test tube containing acid citrate dextrose in a ratio of 9:1 (blood: Acid citrate dextrose), centrifuged at 5000 rpm for 15 min to separate the red blood cells from the platelets and plasma.
Results: The comparison of mean area affected at different duration between the two treatment methods. There has been no significant changes up to 4 weeks. The table shows a significant change after 6 weeks (p<0.05).However in further weeks, the comparison of mean area affected is not significant but shows that the number of patients recovered under PRP method is high.
Conclusion: We found more cases were above 45 years of age. To study the etiology and pathogenesis a much larger group with control is needed. The only significant finding was that among the study groups most patients had associated co-morbidities, that are considered to be causative of chronic ulcers. Time taken for healing was significantly less in PRP group as compared to Conventional method group. The functional outcome of PRP use is also better in comparison to conventional group.