Interpretation of RBC histogram and their correlation with peripheral smear findings in patients of Anemia

Abstract

Background: Anemia, a common blood disorder, is typically diagnosed and classified through various hematological tests, including RBC histograms and peripheral blood smears. This study aims to explore the correlation between RBC histogram patterns and peripheral smear findings in anemic patients, potentially offering insights into more precise diagnostic and classification methods. Methods: This retrospective study analyzed data from 1000 patients diagnosed with anemia. RBC histograms were obtained using standard hematology analyzers and peripheral smears were examined microscopically. Statistical analyses, including correlation coefficients, were used to assess the relationship between histogram patterns and smear findings. Results: Preliminary analysis revealed distinct histogram patterns correlating with specific smear observations, varying across different types of anemia. These patterns showed statistically significant associations with particular smear findings, suggesting potential diagnostic value. Conclusion: This study demonstrates significant correlations between RBC histogram patterns and peripheral smear findings in anemic patients. These findings could contribute to more accurate diagnosis and classification of anemia, enhancing patient management strategies.