“A cross-sectional study correlating clinical and electrophysiological findings in patients with diabetic peripheral neuropathy”

Abstract

Background: Diabetes has become a significant contributor to morbidity in the Indian population. One of the most prevalent long-term effects of diabetes is peripheral neuropathy, which has a high risk of morbidity and mortality. Study aimed to correlate clinical and electrophysiological findings in patients with Type 2 diabetes with clinical symptomatology and signs of peripheral neuropathy
Material & Method: Present cross-sectional study was conducted among patients attending to general medicine OPD and IPD during the period of Jan 2023 to July 2023. All the type 2 diabetes mellitus patients with less than 5yr duration with symptoms and signs of diabetic peripheral neuropathy were included. Patients with more than 5yr of duration of diabetes, chronic renal failure, HIV, pregnancy, malignancy, drug induced alcohol consumption, nutritional deficiency, hypothyroidism and any known collagen vascular disorders were excluded. The blood investigation such as complete blood count and picture, iron profile, HbA1c, blood glucose levels (fasting and post-prandial) were analysed. Nerve conduction test was performed in all the patients and neuropathy severity scale and neuropathy disability score was given to each patient included in the study
Result: A total of 90 patients fulfilling inclusion criteria are included in present study with mean age of 46.52yrs. Among them 68.9% were female patients and 31.1% were male. On assessment of NCS and neuro subdivision, study found a significant higher incidence of abnormal results in patients with neuropathy compared to patients without neuropathy. (p<0.05)
Conclusion: There is significant relation of presence of neuropathy in patients newly diagnosed with type 2 diabetes mellitus. Hence there is requirement of screening of neuropathy signs and symptoms among type 2 diabetes mellitus, to manage the patients at
early to avoid any complications related to neuropathy in near future.