COMPARISON BETWEEN DIPSI AND IADPSG OGTT CRITERIA AS DIAGNOSTIC TEST FOR DIAGNOSIS OF GESTATIONAL DIABETES MELLITUS

Abstract

BackgroundGestational Diabetes causes several maternal and fetal complications.Recognizing and treating diabetes or any degree of glucose intolerance in pregnancy results in lowering maternal and fetal complications.DIPSI (recommended by FOGSI and validated by MoHFW, India)suggesteda single step testing for GDM. Several studies done in India and abroad have suggested conflicting results as compared to the standard IADPSG 75 gm OGTT. This study compares the efficacy of the sensitivity and specificity of DIPSI OGTT as against gold standard IADPSG OGTT criteria. Material and MethodA prospective Diagnostic Evaluation Study carried out on 450 Antenatal patients at a zonal hospital in Eastern India.All participants were subjected to OGTT test by both IADPSG& DIPSI criteria on two separate occasions 7 days apart in the 1st trimester as well as between 24 to 28 weeks.DIPSI results were compared between 75 patients who were positive & 75 patients who were negative by IADPSG criteria. Sensitivity and specificity were calculated.

ResultsSensitivity and Specificity of DIPSI OGTT as against IADPSG OGTT was found to be 90% and 100% respectively. Conclusion
The best approach to screen for Gestational Diabetes is undoubtedly the IADPSG Criteria as recommended by WHO.However in resource poor and developing countries like India, DIPSI criteria is also a good alternative to the IADPSG criteria. Larger multicentric multinational studies are required to establish the diagnostic efficacy of DIPSI as an equally efficacious alternative to the standard IADPSG OGTT.