COMPARATIVE STUDY BETWEEN LOW PRESSURE AND STANDARD PRESSURE PNEUMOPERITONEUM IN LAPAROSCOPIC CHOLECYSTECTOMY ON ALANINE TRANSAMINASE

Abstract

This study is a randomized control trail conducted in CSI Holdsworth Memorial Hospital, Mysore. Study was initiated after taking clearance from Scientific and Ethical committee. Study population consists of 60 patients requiring Laparoscopic Cholecystectomy for benign gall bladder disease. They were divided into two groups, Group-A and Group-B each group consisting of 30 patients. Pre-operative Alanine transaminase (ALT) level was measured in both the groups. Group-A was operated using Low pressure pneumoperitoneum (8-12 mmHg), Group-B was operated using Standard pressure pneumoperitoneum (12-15 mmHg) and duration of the procedure was also noted. Post-operative 24th hour Alanine transaminase (ALT) level was measured. Changes in ALT level in both the groups were compared and reasons for alteration in Liver enzymes were studied