“Assessment and correlation of IMA with Oxidative Stress, Glycemia Status in Diabetic Nephropathy Patients”
DOI:
https://doi.org/10.48047/Keywords:
Diabetic nephropathy, ischemia-modified albumin, type 2 diabetes mellitus, malondialdehyde & vascular injury.Abstract
Background: Increased incidence, severity, and a delayed recovery from stressinduced ischemia contributing to endothelial dysfunction are linked to diabetes problems. This can result in angiopathy, particularly diabetic nephropathy (DN). This study aimed at assessment and correlation of IMA with Oxidative Stress, Glycemia Status in Diabetic Nephropathy Patients. Subjects and Methods: subjects were selected from the Medicine & Nephrology OPD of INDEX Medical College and Hospital for the study and remaining 100 were age and sex matched healthy controls.
Results: IMA shows strongly positive correlation with blood pressure, fasting blood sugar (FBS),PPBG, HbA1c, cholesterol, LDL, triglycerides, serum creatinine and UACR (P<0.05). There is negative correlation between IMA and HDL, GSH.
Conclusion: IMA may function as a sensitive marker of diabetic nephropathy and an indicator of glycemic control.
