PREVALENCE OF HEPATITIS B IN ANTENATAL WOMEN IN A TERTIARY CARE HOSPITAL

Abstract

Hepatitis B contagion occurs worldwide and constitutes a serious public problem. According to WHO, HBV infection is 100 times further murderous than HIV and thus requires further attention. Despite vacuity of a vaccine, HBV infection is aboriginal, estimated to affect 400million people worldwide with veritably high carriage rate (up to 20) particularly in south and East Asia. Worldwide perpendicular transmission remains the most frequent route of infection particularly in aboriginal areas where up to 20 of women of travail age may have HBV. These women constitute a force of perinatal transmission, which is associated with a veritably high rate of regularity (u p to 90) in babies when HBsAg and HBeAg is positive. Transmission of HBV can be averted by vaccination of babies. But despite prophylaxis perinatal transmission of HBV occurs in a small proportion of babies who admit complete active- unresistant immunisation. High motherly viraemia and HbeAg positivity has been associated with intrapartum transmission and vaccine advance. Antiviral remedy during the third trimester of gestation in high riskwomen with habitual HBV infection reduces viral cargo in the mama and drop the threat of transmission, although data are lacking. Safety data in gestation are most robust with LAMIVUDINE and TENOFOVIR compared with other curatives. Hence effective motherly webbing and immunoprophylaxis of babes remains the stylish system of forestallment of mother to child transmission.