High-dose glucose–insulin–potassium has hemodynamic benefi ts and can improve cardiac remodeling in acute myocardial infarction treated with primary percutaneous coronary intervention: From a randomized controlled study

Authors

  • Yanhui Li, Lin Zhang, Lei Zhang, Haiyong Zhang, Nianzhong Zhang, Zhongsu Yang, Mingming Gao, Xinchun Yang, Liang Cui Author

Keywords:

Acute myocardial infarction, glucose–insulin–potassium, reperfusion therapy

Abstract

The concept that the metabolic cocktail, glucose–insulin–potassium (GIK), may protect ischemic cardiomyocytes was fi rst popularized by Sodi-Pallares as a “polarizing agent” in 1962. Opie further proposed the rationale for the use of this metabolic therapy in 1970,

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Published

2010-05-10