Correlation of Haematological Scoring System with C - Reactive Protein and Blood Culture in the Diagnosis and Prognosis of Neonatal Sepsis in A Tertiary Care Hospital, Hyderabad
DOI:
https://doi.org/10.48047/Keywords:
: Correlation, Haematological Scoring System, C-Reactive Protein, Blood Culture, Diagnosis, Prognosis, neonatal sepsis.Abstract
Background: In this study, we wanted to evaluate the diagnostic utility of the Haematological Scoring System of Rodwell et al in correlation with C-Reactive protein and blood culture and assessing its prognostic value, estimate the Haematological Scoring System
of Rodwell et al, compare its correlation with C- reactive protein and blood culture in Neonatal Sepsis, and assess its prognostic value in reflecting the patient’s outcome. Methods: This was a hospital based cross-sectional study conducted among 300 blood samples from clinically suspected cases of neonatal sepsis in the Department of Pathology at Niloufer Hospital, a Tertiary Care Centre in Hyderabad for a period of 2 years, from 2020 to 2022 after obtaining clearance from institutional ethics committee and written informed consent from the study participants.
Results: The sensitivity and specificity of deranged Total Leucocyte count were 58.92% and 84.35% respectively. The sensitivity and specificity of deranged Absolute Neutrophil Count were 86.49% and 46.09% respectively. The sensitivity and specificity of increased Immature Neutrophil Count were 79.46% and 80.87% respectively. The sensitivity and specificity of increased I:T ratio were 80.54% and 83.48% respectively. The sensitivity and specificity of increased I:M ratio were 63.24% and 96.52% respectively. The sensitivity and specificity of Degenerative neutrophil changes were 31.89% and 97.39% respectively. The sensitivity and specificity of reduced platelet count were 65.95% and 55.65% respectively.
