“To study the Molecular characterization of Metallo-beta lactamase gene with Special reference to blaIMP-1 gene in Imipenem Resistant Pseudomonas aeruginosa isolates from Patients of Chronic Suppurative Otitis Media at a Tertiary Care Centre in Uttar Prad

Authors

  • Ambika Bhatiani , Nilam Nigam , Sanjay Nigam , Nashra Afaq, Madhu Yadav , Firoza Bano, Deepak Kumar , Priyanka Saxena , Sahina Hassan, Nusrat Nabi Author

DOI:

https://doi.org/10.48047/

Keywords:

Metallo-ßlactamases, CSOM, CLSI, Molecular characterization,Impenem, blaIMP-1 gene , DNA , PCR

Abstract

Introduction: Persistent suppurative otitis media (CSOM) is a persistent inflammation of the middle ear and mastoid cavity that persists for more than two weeks. Pseudomonas aeruginosa is a common pathogen that causes CSOM. One of the best medications for treating Pseudomonas infections is carbapenem. The development of bacteria resistant to carbapenems is frequently linked
to metallo-ß lactamases. In an effort to stop and propagate resistance, identifying the strains that create MBLs can help guarantee that patients receive the best therapy possible.

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Published

2023-10-06