COMPARISON OF INTRATHECAL NALBUPHINE VS FENTANYL ADDED TO 0.5% HYPERBARIC BUPIVACAINE FOR PERIOPERATIVE ANAESTHESIA AND PERIOPERATIVE/POST OPERATIVE ANALGESIA IN HERNIOPLASTYPROSPECTIVE STUDY

Abstract

Background Nalbuphine is synthetically prepared opioid. It has both agonist and μ antagonist properties(13). When given intrathecally it binds to kappa receptors in the spinal cord and brain. It produces analgesia and sedation via kappa receptors and hence there is no adverse effects mediated by µ receptors. In this study we compared the effectiveness of the two adjuvants nalbuphine and fentanyl added to 0.5% hyperbaric bupivacaine in patients undergoing hernioplasty as Group A and Group B respectively, along with a control group C of intrathecal bupivacaine alone with normal saline.