A Review on Application of Different Polymers in Controlled Release Matrix Formulations
Keywords:
Controlled release, matrix system, synthetic polymer, biodegradable polymerAbstract
Controlled release matrix tablet system is a useful tool for controlled and sustained release dosage forms because of its simplicity, increased safety margin of a potent drug, patient compliance,and low cost than traditional drug delivery systems.In recent years, great attention has laid on replacing the drug's conventional administrationwitha controlled rate delivery system. This kind of drug delivery
has been at the center of research because of its numerous advantages over traditionaldosage.To prevent the drug release rate from the formulation, polymers are being used as the principal tool. Utilization of polymer is currently stretched out to controlled release drug delivery system. Polymers are derived either from natural source or synthesized chemically. This review aims to discuss
different materials used to prepare matrix tablets and various types of matrix systems currently being used, and the matrices' drug release mechanism.
