IMPACT OF GLYCEMIC CONTROL ON TRIGLYCERIDE GLUCOSE INDEX AND ATHEROGENIC INDICES : ASSESSING ATHEROGENIC RISK IN TYPE 2 DIABETES MELLITUS

Abstract

INTRODUCTION : Type 2 Diabetes Mellitus (T2DM) is a prevalent chronic metabolic disorder that is associated with a variety ofcomplications, particularly cardiovascular disease. T2DM is characterized by insulin resistance, beta-cell dysfunction and abnormal lipid metabolism, all of which contribute to the increased risk of cardiovascular morbidity and mortality in affected individuals.While glycemic control, typically evaluated through markers like HbA1c, is essential in managing T2DM, it may not fully capture the overall cardiovascular risk. Alternative biomarkers, such as the Triglyceride-Glucose (TyG) index and the Atherogenic Index of Plasma (AIP)  have been suggested as valuable tools for assessing cardiovascular risk in diabetic patients, particularly in relation to insulin resistance and lipid metabolism.