Long Term Glucocorticoids effects on Underlying Dermatological Conditions: A Tertiary Care Center Study

Abstract

Background: In Dermatology, corticosteroids (CSs) are widely prescribed in various 
formulations to tailor the therapy according to severity of the condition, area of involvement, and 
patient’s age. CSs, are associated with a number of serious adverse effects, particularly with 
long-term use.  
Aims: To study the relationship of adverse drug reactions (ADR) of long term glucocorticoids 
(GC) with age, sex, smoking, alcoholism, underlying dermatologic conditions and co-existing 
medical disorders.  
To study them in relation to the  musculoskeletal system, metabolic *** levels and eye.   
Material and Methods: This was a prospective study done on 130 patients on  glucocorticoid 
therapy for more than 1 month duration during a period of 2  years in the department of 
dermatology over a tertiary care centre. Thorough clinical examination, and relevant 
investigations were done.