Species Distribution, Virulence factors and Antibiotic Sensitivity Pattern of Coagulase Negative Staphylococci Isolated from the Clinical Specimens in a Tertiary Care Centre

Abstract

Coagulase-Negative Staphylococci (CoNS) are generally less virulent but have emerged as 
significant pathogens in healthcare settings, particularly in immunocompromised patients or 
those with indwelling medical devices. Coagulase-Negative Staphylococci (CoNS) strains are 
increasingly resistant to various antibiotic classes, including macrolides, aminoglycosides, 
and fluoroquinolones, along with beta-lactam group, posing challenges in clinical treatment. 
the current study aims to investigate the occurrence, species distribution, antibiogram, 
virulence factors, of Coagulase-Negative Staphylococci (CoNS) isolates obtained from 
clinical specimens in a tertiary care centre.